کنفرانس بین المللی میکروالکترونیک ایران

صفحه اصلی / هفتمین کنفرانس بین المللی میکروالکترونیک ایران

Surface Plasmon Resonance-Based Biosensing for Vibrio Cholerae Detection: A Comprehensive Review

نویسندگان :

Zahra Davarjou¹ Mohammad Hadi Shahrokh Abadi²

1- دانشگاه حکیم سبزواری 2- دانشگاه حکیم سبزواری

کلمات کلیدی :

Surface Plasmon Resonance،Vibrio Cholerae،Optical Biosensor،Refractive Index،Point-of-Care Testing

چکیده :

Cholera, an acute diarrheal disease caused by Vibrio Cholerae (VC) bacterium, remains a global health threat, especially in regions with poor sanitation. Rapid, on-site detection is crucial for curbing outbreaks, yet traditional methods are time-consuming and lab-dependent. Surface Plasmon Resonance (SPR) biosensors emerge as a transformative solution, enabling real-time, label-free pathogen detection with high sensitivity. By exciting electron oscillations at a metal-dielectric interface, SPR measures refractive index shifts from bacterial binding, producing a detectable resonance angle dip. This review explores cutting-edge SPR platforms, from prism-based to nanomaterial-enhanced systems, for portable, field-deployable cholera monitoring. These advances promise to revolutionize outbreak response through point-of-care diagnostics, water safety testing, and public health surveillance.